A Functional Cure For Diabetes

Incubator photo

Research Goals

Attain a Biological License for Islet Transplantation

The Chicago Diabetes Project is currently conducting a phase III licensure trial in islet transplantation to successfully apply for a biological license for islet transplantation. This will allow islet transplantation to be recognized as standard medical care for brittle type I diabetic patients, and is mandatory for reimbursement by medical insurances.

Study Encapsulated Human Islet Transplants in Humans

We are also planning a phase I/II clinical trial with encapsulated human islet allotransplantation (link to definition) in brittle type I diabetic patients. This will be the first clinical trial of this nature conducted in an academic center in the US, and will ultimately answer the question whether the concept of microencapsulation of islet grafts works in humans or not.

Develop an Unlimited Source of Islet Cells

To control patients' blood-sugar levels, the Chicago Diabetes Project plans to produce an unlimited source of islet cells in the laboratory that are suitable and safe for transplantation in humans. By delivering a limitless source of pancreatic islet cells, members of the Chicago Diabetes Project team offers hope to the millions of patients throughout the world a chance at living a normal and healthy life free of managing and controlling diabetes.