Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques

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Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques

Abstract The transplantation of pancreatic islet cells could restore glycaemic control in patients with type 1 diabetes. Microspheres for islet…

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Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes

Abstract AIMS: Changes in the islet vasculature have been implicated in the regulation of β-cell survival and function during the…

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Noninvasive Tracking of Encapsulated Insulin Producing Cells Labelled with Magnetic Microspheres by Magnetic Resonance Imaging

Abstract Microencapsulated islets are usually injected free-floating into the peritoneal cavity, so the position of the grafts remains elusive after…

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Proproliferative and antiapoptotic action of exogenously introduced YAP in pancreatic β cells

Abstract: Loss of functional pancreatic β cells is a hallmark of both type 1 and 2 diabetes. Identifying the pathways…

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Based in Chicago at the University of Illinois Hospital and Health Services, the Chicago Diabetes Project is a collection of scientists, researchers, physicians and surgeons spanning the globe who have a two-fold mission to cure diabetes.

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